Neuroglycobiology & Myelin Integrity
Neuroglycobiology & Myelin Integrity
Articles on the role of brain-specific glycosylation, O-mannose glycans, and glycobiology in myelin structure, node of Ranvier stability, and axonal conduction.
neuroglycobiology myelin integrity8 hours ago4 min
Brain Sugar Glycans Maintain Nerve Signal Speed by Stabilizing Node of Ranvier Architecture
A new study reveals that MGAT5B-synthesized branched O-mannose glycans are essential for anchoring neurofascin 186 at nodes of Ranvier, ensuring rapid saltatory conduction in myelinated axons.