AI & Brain-Gut-Bone Axis
AI & Brain-Gut-Bone Axis
Articles on the emerging brain-gut-bone axis, including how psychological stress accelerates hematopoietic stem cell aging via gut microbiome signaling, and the implications for aging, immunity, and bone health.
ai brain gut bone axisJul 3, 20263 min
Stress Silences Two Brain Regions, Triggering a Gut-Bone Marrow Cascade That Ages Immune Stem Cells
A new study reveals that chronic stress suppresses the medial prefrontal cortex and periaqueductal gray, collapsing gut Lactobacillus reuteri and depleting spermidine—leading to mitochondrial failure and premature aging in hematopoietic stem cells.