Gene Therapy & Neurodegeneration
Gene Therapy & Neurodegeneration
Articles on gene therapy approaches for neurodegenerative diseases, including viral vector delivery, neuroprotective gene overexpression, and therapeutic strategies targeting TDP-43, Alzheimer's, FTD, and ALS.
gene therapy neurodegenerationJun 29, 20264 min
Building Neurons from the Inside Out: How SynCav1 Gene Therapy Rewrites the Neurodegeneration Playbook
A UC San Diego study demonstrates that systemic delivery of the SynCav1 gene via a modified virus crosses the blood-brain barrier to boost caveolin-1 expression, preserving neurons against TDP-43–induced cognitive decline across FTD, ALS, and Alzheimer's disease models.