Neurobiology of Sleep & Arousal
Neurobiology of Sleep & Arousal
Articles on the neurobiological mechanisms of sleep, arousal, hyperarousal disorders, and the role of molecular regulators like microexons and cAMP signaling in behavioral states.
neurobiology of sleep arousalJun 30, 20267 min
Your Brain's Broken Thermostat: How Tiny RNA Glitches Lock You in Permanent Insomnia
A groundbreaking study reveals that mis-spliced neuronal microexons trigger a permanent cAMP spike — turning the brain's arousal system into a runaway heater, causing insomnia, sensory overload, and hyperactivity. This isn't just a sleep disorder. It's a molecular malfunction with deep roots in autism and schizophrenia.